“The Sub tuum praesidium is probably the oldest Christian prayer dedicated to the Blessed Virgin Mary. This prayer was long used in both Eastern and Western rites…” Read much more and see a 3rd century papyrus fragment, at the New Liturgical Movement.
Sub tuum praesidium confugimus, Sancta Dei Genetrix. Nostras deprecationes ne despicias in necessitatibus1, sed a periculis cunctis libera nos semper, Virgo gloriosa et benedicta. Amen.
We fly to thy patronage, O holy Mother of God; despise not our petitions in our necessities, but deliver us always from all dangers, O glorious and blessed Virgin. Amen.